Enterprise Software startups in San Francisco

DepthFirst

San Francisco

depthfirst is an applied AI lab dedicated to securing the world's software, focusing on AI-native security as software underpins modern civilization and exploits are expected to rise with AI proliferation.

Campfire

San Francisco

Campfire is an AI-native ERP for mid-size and enterprise companies to close fast and scale faster. Based in San Francisco, it is backed by Accel, Foundation Capital, Y Combinator and Capital49(Airwallex), serving 50 to 5,000-employee firms

Listen Labs

San Francisco

Listen is an autonomous market researcher that uses AI to design interviews, recruit participants, and analyze responses, delivering insights in hours rather than weeks, 24/7. Trusted by Google, Microsoft, SKIMS, Nestlé, and hundreds of ent

Bretton AI

San Francisco

Bretton AI (formerly Greenlite AI) builds AI agents for financial crime compliance, helping banks and fintechs automate AML and KYC work.

Giga

San Francisco

Giga provides enterprise customer support by deploying AI agents, handling over 1 million tickets monthly, and counting industry leaders like Postman and Zepto among its clients, with rapid scaling backed by investors including Garry Tan and Nexus Venture Partners.

Zip

San Francisco

Zip, founded in 2020, pioneered procurement orchestration and leads $50B+ TAM, serving enterprises such as Instacart, Sephora, Reddit, Lyft, and brands like Airbnb, Facebook, Google. Valued at $2.2B with $370M in funding from Y Combinator,

Artisan

San Francisco

Artisan builds AI employees called Artisans and aims to replace the SaaS stack with a single integrated platform, starting with outbound sales; it consolidates every sales SaaS into one platform, framing it as next Industrial Revolution and

Alembic

San Francisco

Alembic provides causation analytics on proprietary data at scale, answering questions generic AI cannot. It serves Fortune 500 clients including Nvidia, Delta Air Lines, Mars; it operates one of the world's fastest private supercomputers a

Wordware

San Francisco

Wordware offers a web-hosted IDE that lets non-technical domain experts collaborate with AI engineers to build task-specific AI agents, treating prompting as a programming language for natural language programming and agent orchestration.

AfterQuery

San Francisco

AfterQuery builds datasets and experimentation to advance frontier LLM and AI-agent workflows, constructing complex data-infrastructure for agentic and hard-reasoning tasks. It partners with five AI labs and is YC's infrastructure partner, led by teams from top banks and quant firms.

Further

San Francisco

FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15

FurtherAI

San Francisco

FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15

Fulcrum Tech

San Francisco

The company develops an AI platform that automates administrative tasks for insurance brokerages, with strong penetration in enterprise brokerages. It recently raised a Series A and aims to expand in the $1.5 trillion insurance market.

Vultron

San Francisco

Vultron helps federal contractors win contracts by delivering compliant proposal drafts and compressing weeks of work into days. It is trusted by 400+ federal contractors and has enabled $2.2B in contract wins, using proprietary models trai

Automat

San Francisco

Automat is a generative AI platform that creates and scales end-to-end automations, redefining Enterprise AI Agents, RPA, and Intelligent Document Processing; it serves some of the world's largest companies and claims 10x speed and lower co

Momentic

San Francisco

**The AI-native automated testing platform** Momentic is the modern alternative to Selenium, Cypress, and Playwright. We help software companies ship faster with reliable end-to-end tests that write themselves. World-class engineering team

Simple AI

San Francisco

Simple AI builds enterprise-grade voice AI agents to automate customer conversations at scale, handling millions of calls for brands like Doordash, xAI, and Omaha Steaks. Backed by Y Combinator and notable investors, the lean startup aims t

Eragon

San Francisco

Eragon is an AI Operating System for enterprises that serves as a reasoning engine, learning and acting across the organization, embedding into workflows to unify data, people, and processes into a context-aware workspace for billion-dollar decisions.

Brainbase

San Francisco

Brainbase Labs is building an AI Workforce by deploying AI agents that act as employees for front-line support to back-office tasks. Backed by top investors and with a multinational team, it has 150+ live deployments across automotive, hosp

Cogent Security

San Francisco

Cogent develops AI-powered vulnerability management solutions for enterprises, aiming to create an AI Taskforce for Vulnerability Management to boost efficiency and accelerate risk reduction. It is trusted by brands and led by executives fr

Unsiloed AI

San Francisco

Unsiloed AI provides production-grade APIs that ingest, parse, structure, and split documents into Markdown and JSON, preserving hierarchy and domain-specific context for Finance, Legal, and Healthcare workflows, enabling reliable AI/LLM us

Eloquent AI

San Francisco

Eloquent AI designs autonomous AI agents for regulated industries, enabling real-time compliance and reducing hallucinations in high-stakes interactions, serving financial institutions and insurers worldwide from its San Francisco headquart

Altara

San Francisco

Altara is a San Francisco startup building an AI co-scientist for the physical world to accelerate breakthroughs in semiconductors, batteries, materials, chemicals, and aerospace, aiming to define a new AI-for-science category; backed by Gr

Abacus

San Francisco

Abacus builds AI agents to automate tedious accounting workflows, redefining how accounting firms operate. It serves large enterprise clients, generates meaningful revenue, and is led by a two-person founding team backed by top-tier investo

Lumena

San Francisco

Lumena empowers domain experts to build AI-powered enterprise applications, enabling humans and AI to collaborate across systems such as Salesforce, NetSuite, and HubSpot. Its design partners include mid-market and enterprise companies in f

Onos Health

San Francisco

Onos Health is a San Francisco-based early-stage startup building an AI-powered platform to reduce waste in U.S. healthcare spending by aligning providers and payers, with a $6M seed round, live partnerships with major health plans, and exp

Turgon

San Francisco

At Turgon, a San Francisco and New Delhi startup founded by serial entrepreneurs, combines AI agents with human-in-the-loop solutions to build, integrate, and run the enterprise IT stack, tapping into a $1.5 trillion IT services market.

Crustdata

San Francisco

A VC-backed data company delivering real-time company and people data enrichment via APIs, founded by Chris Pisarski, Abhilash Chowdhary, and Manmohit Grewal, with 15 engineers and offices in New York City and San Francisco, building reliab

XOXO AI

San Francisco

XOXO AI is a stealth research lab building consumer social AI that predicts user needs and fulfills them without prompts, aiming to democratize intelligent interfaces. It is assembling engineers, designers, and researchers to lead the next

Carma (YC W24)

San Francisco

Carma is a fastest-growing fleet management software company powering large US fleets, including Fortune 500 clients. It raised a $5.5 million seed round from Soma Capital, Y Combinator, and Superhuman founders, claiming to save thousands o

Reflex

San Francisco

Reflex is an open-source framework and hosted platform that helps Python developers build, deploy, and manage web apps, backed by an ecosystem of tools and services to speed development while preserving flexibility; founded by open-source m

Magnetic

San Francisco

Magnetic is building an AI tax preparer for CPA firms, publicly launched in 2025, with $5.2M in funding and ARR in the hundreds of thousands across dozens of firms, aiming to automate tax prep with higher accuracy and better workflow.

Tomex.ai

San Francisco

Tomex AI builds AI for enterprise supply chains, helping Fortune 500 organizations enforce negotiated terms and prevent tens of millions in annual losses. It is rapidly scaling and will engage Fortune 500 firms across CPG, retail, and healt

Amari AI

San Francisco

The company provides AI-powered automation for customs clearance processes tailored to customs brokers, freeing them from repetitive work to focus on relationships and growth; it has helped brokers clear over $150 million in goods.

Klarity

San Francisco

Klarity Health provides high-quality, worry-free and low-cost telehealth services, ensuring comprehensive care is within reach. Whether you're seeking mental health support, weight management, or counseling and therapy, Klarity is your trusted marketplace for health and well-being. We have facilitated over 350,000 telehealth visits and are trusted by 80,000+ patients and 400+ medical specialists. Check out our 5-star ratings: https://www.reviews.io/company-reviews/store/helloklarity

Remy

San Francisco

Remy builds autonomous AI product teams, beginning with design agents, to provide a 24/7 visual exploration and brainstorming partner for software teams, with the aim of becoming an autonomous teammate that ideates, designs, and ships softw

Ivo

San Francisco

Ivo develops generative AI products for legal teams and an AI-native platform that automates contract review and other legal work, helping teams reduce time, effort, and cost and accelerate time-to-close.

11x

San Francisco

11x builds fully autonomous digital workers that automate specific jobs end-to-end, aiming to sell work, not software; a pioneer in digital workers with hundreds of customers including Brex, Otter AI, and Hasura, and millions in revenue in