AI/ML startups in San Francisco

The Bot Company

San Francisco

The Bot Company builds household robots to give people back time, pursuing in-house AI, software and hardware. It plans to deploy millions at home before expanding, and has raised $300M, including a $150M Greenoaks-led round, valuing the co

Decagon

San Francisco

Decagon is a leading conversational AI platform delivering concierge customer experiences with AI agents across chat, email, and voice in any language. It serves brands like Hertz, Eventbrite, Duolingo, and Oura and is backed by Accel and A

Decart

San Francisco

Decart provides efficient systems-level AI infrastructure that dramatically accelerates training and inference of the largest generative models, enabling Decart to train its own foundational interactive models and offer real-time access to

LMArena

San Francisco

LMArena, created by UC Berkeley researchers, is an open platform for accessing and comparing leading AI models, where users rate responses and help build a public, real-world leaderboard to increase transparency in AI progress.

Listen Labs

San Francisco

Listen is an autonomous market researcher that uses AI to design interviews, recruit participants, and analyze responses, delivering insights in hours rather than weeks, 24/7. Trusted by Google, Microsoft, SKIMS, Nestlé, and hundreds of ent

Bretton AI

San Francisco

Bretton AI (formerly Greenlite AI) builds AI agents for financial crime compliance, helping banks and fintechs automate AML and KYC work.

David AI

San Francisco

David AI builds audio datasets through R&D; founded in 2024 by former Scale AI engineers, it counts FAANGs and AI labs among customers and raised a $50M Series B from Meritech, NVIDIA and others, achieving seven-figure revenue in six months

Edison Scientific

San Francisco

Edison Scientific, spun out from FutureHouse in 2025, accelerates scientific discovery by building and commercializing AI agents for science, pursuing an AI Scientist to scale autonomous research and tackle challenges such as drug developme

Stand Insurance

San Francisco

The company protects and insures homes against wildfire and hurricane risks by applying physics and AI to model true property risk, enabling more homes to be insurable.

Artisan

San Francisco

Artisan builds AI employees called Artisans and aims to replace the SaaS stack with a single integrated platform, starting with outbound sales; it consolidates every sales SaaS into one platform, framing it as next Industrial Revolution and

Noon

San Francisco

Noon (formerly Weaver) is an AI-native product design tool that links design and code so product teams can go from idea to shipped interface.

Counsel Health

San Francisco

Counsel is building an AI-driven healthcare practice to scale care delivery and provide rapid, personalized medical advice, leveraging partnerships with leading healthcare organizations and collaborative clinician–AI models; founded 2023, r

Delve

San Francisco

Delve is an AI-native compliance company helping 700+ fast-growing firms achieve SOC 2, HIPAA, ISO, GDPR, and other standards in days, not months; trusted by Lovable, Bland, and Wispr Flow, and building an AI-native platform to automate com

E2B

San Francisco

E2B is a Series A startup building the next hyperscaler for AI agents. It has seven figure revenue and has raised over $32M from investors including Insight Partners, serving Perplexity, Hugging Face, Manus, and Groq in San Francisco and Pr

Casca

San Francisco

Casca is building AGI for banking, replacing legacy systems with AI-native tech that automates 90% of manual work. It emphasizes responsible AI with human-in-the-loop monitoring and is backed by Y Combinator, Peterson Ventures, The Sarah Sm

Alembic

San Francisco

Alembic provides causation analytics on proprietary data at scale, answering questions generic AI cannot. It serves Fortune 500 clients including Nvidia, Delta Air Lines, Mars; it operates one of the world's fastest private supercomputers a

Wordware

San Francisco

Wordware offers a web-hosted IDE that lets non-technical domain experts collaborate with AI engineers to build task-specific AI agents, treating prompting as a programming language for natural language programming and agent orchestration.

AfterQuery

San Francisco

AfterQuery builds datasets and experimentation to advance frontier LLM and AI-agent workflows, constructing complex data-infrastructure for agentic and hard-reasoning tasks. It partners with five AI labs and is YC's infrastructure partner, led by teams from top banks and quant firms.

Judgment Labs

San Francisco

Judgment Labs provides infrastructure for Agent Behavior Monitoring (ABM) to observe post-deployment autonomous-agent behavior at scale, serving hundreds of teams. It has raised over $30 million from notable investors and positioned as a le

FurtherAI

San Francisco

FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15

Unify

San Francisco

Unify is an AI-first go-to-market platform that treats growth as a science, powering pipeline for leading teams such as Airwallex, Cursor, Perplexity, Together AI, and Guru. Founded Jan 17, 2023 by Austin Hughes and Connor Heggie, with a Li

Moonlake

San Francisco

The company builds multimodal reasoning models, developing AI systems that can reason across multiple modalities and integrate diverse data types. This focus positions it in a technically advanced area of AI development.

Indent

San Francisco

Indent is a platform for large engineering teams, used for incident response, code review, and data analysis with minimal setup. It provides a cloud AI software engineer that handles the entire job, including real-world tasks like analyzing

Mem0

San Francisco

Mem0 provides a universal, self-improving memory layer for LLM applications, enabling personalised AI experiences while reducing costs and boosting user delight. It markets itself as "The memory layer for Personalized AI."

Sauron

San Francisco

Sauron provides residential security via autonomous robots and cars, led by alumni of Zipline, Tesla, Apple, and Google. Incubated by Kevin Hartz and Atomic, it has raised rounds totaling at least $40M from investors including A*, 8VC, and

Alex (formerly Apriora)

San Francisco

Alex AI builds the future of hiring with an autonomous recruiter that conducts real-time video interviews, asking employer-selected or job-based questions and personalized follow-ups to speed hires and improve signals; it supports thousands

Automat

San Francisco

Automat is a generative AI platform that creates and scales end-to-end automations, redefining Enterprise AI Agents, RPA, and Intelligent Document Processing; it serves some of the world's largest companies and claims 10x speed and lower co

Archil

San Francisco

Archil connects AI applications to data resources, including model training, agents, and sandboxes, enabling data access for AI development and experimentation. It positions itself as the connector between AI tools and the data they require

Browser Use

San Francisco

The company specializes in animating web agents, bringing them to life as living entities on the web.

ComfyUI

San Francisco

ComfyUI is a San Francisco-based, open-source, node-based engine for generating visual AI content, billed as the world’s leading visual AI platform with a modular system and a community of millions of users, 60k GitHub stars, and thousands

Phonely

San Francisco

Phonely develops voice AI technology to improve customer support and enable doctors to see more patients, while reducing hold times. It positions itself as a leader in intelligent, scalable customer communication and aims to redefine how bu

Eigen

San Francisco

Eigen is building a consumer social company focused on peer-like connections rather than an assistant, aiming to redefine social experience with intuitive product design and human-centered interactions.

Hark

San Francisco

Hark builds an end-to-end AI automation system—from workflow ingestion to production monitoring—plus services that accelerate deployment 10x; founded by Obaid Khan and Tim Lee, bringing operator credibility from Motive, Miso Media, and Code

Simple AI

San Francisco

Simple AI builds enterprise-grade voice AI agents to automate customer conversations at scale, handling millions of calls for brands like Doordash, xAI, and Omaha Steaks. Backed by Y Combinator and notable investors, the lean startup aims t

Tamarind Bio

San Francisco

Tamarind provides access to AI-powered drug discovery for scientists, used by thousands from pharma, biotech, and academia, serving a broad, cross-industry research community.

Mandolin

San Francisco

Mandolin is building last-mile delivery infrastructure to speed development and delivery of cutting-edge drugs (cell/gene therapies, biologics), aiming to extend healthy lifespans by shortening time to patient access; backed by SignalFire,

ZeroPath

San Francisco

ZeroPath, founded by security researchers formerly from Tesla and Google, helps developers ship secure code faster with a developer-friendly solution that changes how teams approach application security.

Dedalus Labs

San Francisco

Dedalus Labs provides an MCP gateway and servers, unifying the AI agents ecosystem with a drop-in API. It enables users to go from idea to production in a single click, mixing models from any vendor with MCP marketplace tools.